We engineer biological systems by means of computers to make transformative tools and medicines


The de la Fuente Lab is based in the Department of Bioengineering and the Departments of Microbiology, and Psychiatry in the Perelman School of Medicine at the University of Pennsylvania. We draw on protein design, synthetic biology, bioengineering, microbiology, and computational biology to establish foundational platforms for the engineering of biological systems. We use the principles and tools of these diverse disciplines to tackle a wide range of global health challenges. Our overarching goal is to find solutions to the world’s hardest biomedical problems, including antibiotic resistance, infectious diseases, cancer, and microbiome engineering.

Current research projects in the lab include: