Mining human microbiomes reveals an untapped source of peptide antibiotics

Introduction In response to the alarming rise of drug-resistant bacteria, which has far outpaced the development of conventional antibiotics, our latest research published in Cell has identified a promising new avenue for antibiotic discovery within the human microbiome. As global health faces a severe threat from antibiotic resistance, our team in collaboration with Ami S. […]

Continue reading

AI discovers antibiotics in extinct organisms

Introduction Antimicrobial resistance (AMR) is one of the greatest threats facing humanity today, making the need for new antibiotics more critical than ever. Traditional approaches to antibiotic discovery are painstakingly slow, often taking years to identify preclinical candidates. In a groundbreaking study published in Nature Biomedical Engineering, our team introduces APEX, a new AI model […]

Continue reading

AI-Driven Discovery of Nearly 1 Million New Antibiotics in the Global Microbiome

Introduction Antimicrobial resistance is one of the greatest threats facing humanity and novel antibiotics are urgently needed. In a recent study published in Cell, our team, along with fantastic collaborators, leveraged computational techniques to accelerate the search for new antimicrobial compounds, specifically focusing on antimicrobial peptides (AMPs). By employing advanced genome mining methods, we identified […]

Continue reading